Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35612 | 0.98 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9301854 | 0.93 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18784855 | 0.92 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9764018 | 0.92 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19239960 | 0.92 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5202786 | 0.91 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13334671 | 0.90 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27039068 | 0.90 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4883019 | 0.90 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5575866 | 0.90 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-2125833-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2125834-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |