Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764018 | 0.93 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35612 | 0.92 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27039068 | 0.91 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL395578 | 0.91 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9301854 | 0.88 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19239960 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18784855 | 0.87 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13334671 | 0.85 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4883019 | 0.84 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5575866 | 0.84 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789821-B1 | SILICONE HYDROGEL CONTACT LENSES | COOPERVISION INT HOLDING CO LP (BB) | 2019-04-10 | — | — | EP | disclosed |
| US-9322958-B2 | Silicone hydrogel contact lenses | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2016-04-26 | — | — | US | disclosed |
| US-20150219795-A9 | Silicone Hydrogel Contact Lenses | COOPERVISION INTERNATIONAL LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20140200286-A1 | Silicone Hydrogel Contact Lenses | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2014-07-17 | — | — | US | disclosed |
| US-8614261-B2 | Silicone hydrogel contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY LP (BB) | 2013-12-24 | — | — | US | disclosed |
| US-8367746-B2 | Silicone hydrogel contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY (BB) | 2013-02-05 | — | — | US | disclosed |
| US-20120252925-A1 | Silicone Hydrogel Contact Lens | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2012-10-04 | — | — | US | disclosed |
| EP-1789821-A2 | SILICONE HYDROGEL CONTACT LENSES | ASAHIKASEI AIME CO., Ltd. (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-20070066706-A1 | Silicone hydrogel contact lens | COOPERVISION, INC. (US) | 2007-03-22 | — | — | US | disclosed |
| US-20060063852-A1 | Silicone hydrogel contact lens | ASAHIKASEI AIME CO. LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| WO-2006026474-A2 | SILICONE HYDROGEL CONTACT LENSES | ASAHIKASEI AIME CO. LTD. (JP) | 2006-03-09 | — | — | WO | disclosed |