Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395578 | 0.98 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9301854 | 0.95 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18784855 | 0.94 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9764018 | 0.94 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19239960 | 0.94 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5202786 | 0.92 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13334671 | 0.92 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27039068 | 0.92 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4883019 | 0.91 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5575866 | 0.91 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600820-B2 | Photocurable composition with high silicon content | CANON KABUSHIKI KAISHA (JP) | 2026-04-14 | — | — | US | claimed |
| EP-4689269-A1 | SILICONE - (METH)ACRYLATE COPOLYMER EMULSION AND PREPARATION THEREOF AND USE OF THE EMULSION TO IMPART OIL REPELLENCY TO TEXTILES | Dow Silicones Corporation (US) | 2026-02-11 | — | — | EP | claimed |
| US-20250368802-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY | CANON KK (JP) | 2025-12-04 | — | — | US | claimed |
| EP-4384560-B1 | SILICONE-(METH)ACRYLATE COPOLYMER EMULSION FORMULATION FOR TEXTILE TREATMENT | DOW SILICONES CORP (US) | 2025-11-05 | — | — | EP | claimed |
| WO-2025090189-A1 | SILICONE – (METH)ACRYLATE COPOLYMER EMULSION AND PREPARATION THEREOF AND USE OF THE EMULSION TO IMPART OIL REPELLENCY TO TEXTILES | DOW SILICONES CORPORATION (US) | 2025-05-01 | — | — | WO | claimed |
| EP-4526381-A1 | SILICONE HYDROGEL CONTACT LENSES | Interojo Inc. (KR) | 2025-03-26 | — | — | EP | claimed |
| US-20240199816-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT | CANON KABUSHIKI KAISHA (JP) | 2024-06-20 | — | — | US | claimed |
| WO-2024123531-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT | CANON KABUSHIKI KAISHA (JP) | 2024-06-13 | — | — | WO | claimed |
| US-20240159938-A1 | Compositions for Ophthalmologic Devices | JOHNSON & JOHNSON VISION CARE, INC. | 2024-05-16 | — | — | US | claimed |
| WO-2023224184-A1 | SILICONE HYDROGEL CONTACT LENSES | INTEROJO INC. (KR) | 2023-11-23 | — | — | WO | claimed |
| US-5962548-A | SOFT CONTACT LENSES | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-0940693-A2 | Soft contact lenses | Johnson & Johnson Vision Products, Inc. (US) | 1999-09-08 | — | — | EP | claimed |
| US-5770669-A | Silcone-containing polymer having oxygen permeability suitable for ophalmic applications | CIBA VISION CORPORATION (US) | 1998-06-23 | — | — | US | claimed |
| EP-0796448-A1 | SILICONE-CONTAINING POLYMER SUITABLE FOR OPHTHALMIC APPLICATIONS | Novartis AG (CH) | 1997-09-24 | — | — | EP | claimed |
| WO-1996018122-A1 | SILICONE-CONTAINING POLYMER SUITABLE FOR OPHTHALMIC APPLICATIONS | NOVARTIS AG (CH) | 1996-06-13 | — | — | WO | claimed |
| EP-0277555-B1 | COPOLYMERS WITH 0-NITROCARBINOL ESTER GROUPS, AND PROCESS FOR PREPARING TWO-LAYER RESISTS AND SEMICONDUCTOR DEVICES | BASF Aktiengesellschaft (DE) | 1992-04-08 | — | — | EP | claimed |
| US-5023159-A | Encapsulated electrophotographic toner compositions | XEROX CORPORATION (US) | 1991-06-11 | — | — | US | claimed |
| US-4988788-A | Room temperature-curable coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | claimed |
| US-4808682-A | BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
| EP-0277555-A2 | Copolymers with 0-nitrocarbinol ester groups, and process for preparing two-layer resists and semiconductor devices | BASF Aktiengesellschaft (DE) | 1988-08-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600820-B2 | Photocurable composition with high silicon content | BIRC2, ACP1, IRS1 | TSHR 4173/4885THRB 4666/4885POLB 3409/4885 |
| US-20240159938-A1 | Compositions for Ophthalmologic Devices | PDE6D, CRYAB, PDE6H | TSHR 3951/4885THRB 4153/4885POLB 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.