Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18627186 | 0.97 | MAPT (0.58) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5074997 | 0.89 | MAPT (0.51) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19830567 | 0.87 | MAPT (0.74) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL395599 | 0.87 | MAPT (0.74) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15685932 | 0.87 | NPC1 (0.52) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17998030 | 0.83 | SRD5A2 (0.68) | MAPTLMNAMAPK1ALDH1A1ALOX15 | |
| SCHEMBL12362759 | 0.83 | TUBB4A (0.72) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25471518 | 0.83 | MAPT (0.68) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL51509 | 0.81 | RXFP1 (0.79) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16179592 | 0.81 | GABRA1 (0.52) | MAPTMAPK1ALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359176-B1 | Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups | BAYER MATERIALSCIENCE AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-6825312-B2 | POLYCARBONATESTER COPOLYMER MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| US-20040030090-A1 | Polycarbonates, polyester carbonates and polyesters with special branched terminal groups | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-1359176-A2 | Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups | Bayer Aktiengesellschaft (DE) | 2003-11-05 | — | — | EP | disclosed |