Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MITF | O75030 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760093 | 0.88 | PPARA (0.46) | SMN1; SMN2LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL3760095 | 0.88 | PPARA (0.46) | SMN1; SMN2LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL3962122 | 0.86 | PPARA (0.50) | LMNAL3MBTL1HTTTBXA2RPPARA | |
| SCHEMBL3764186 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL3959737 | 0.83 | PPARA (0.40) | L3MBTL1ALDH1A1MAPTTBXA2RPPARA | |
| SCHEMBL3962164 | 0.82 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL3961525 | 0.82 | TBXAS1 (0.44) | SMN1; SMN2LMNAHTTALDH1A1TBXA2R | |
| SCHEMBL3957381 | 0.80 | PPARA (0.45) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL3961695 | 0.80 | PPARA (0.41) | NPC1RAB9APPARAPPARG | |
| SCHEMBL3959581 | 0.80 | PPARA (0.49) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |