Taxifolin

Taxifolin

SCHEMBL39570

O=C1c2c(O)cc(O)cc2OC(c2ccc(O)c(O)c2)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 1.00
ALOX15 P16050 4/20 1.00
MAPT P10636 3/20 1.00
HSD17B10 Q99714 3/20 1.00
RECQL P46063 2/20 1.00
SOST Q9BQB4 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
KDM4E B2RXH2 2/20 1.00
GAA P10253 2/20 1.00
ALOX12 P18054 2/20 1.00
HIF1A Q16665 2/20 1.00
POLB P06746 1/20 1.00
CYP1A2 P05177 1/20 1.00
NFKB1 P19838 1/20 1.00
MAPK1 P28482 1/20 1.00
SYNJ2 O15056 3/20 0.75
APP P05067 1/20 0.75
XDH P47989 2/20 0.67
IDO1 P14902 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taxifolin SCHEMBL29390633 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL30300501 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL30631315 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29361519 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL13241264 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL7628142 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL296323 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29368246 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Epitaxifolin SCHEMBL31575455 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL1707803 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10255 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075591-A Application of sour cherry powder and celery seed powder composition and compound containing composition 2026-05-26 CN claimed
CN-118576643-B Red yeast fermentation product for reducing nodules Qianjiexiao (Zhejiang) Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075473-A Use of taxifolin in resisting radiation injury 2026-05-26 CN claimed
CN-122056842-A Tablet for assisting in protecting liver injury and improving liver fat metabolism and preparation method thereof 瀚天生物(北京)科技有限公司 2026-05-19 CN claimed
CN-118252866-B Method for extracting and purifying Phellinus linteus fruiting body phenols in series and application of Phellinus linteus fruiting body phenols in uric acid regulation 湖北省农业科学院农产品加工与核农技术研究所 2026-05-19 CN claimed
CN-122056334-A Daily ration composition for improving growth performance and health of weaned pigs and application of daily ration composition 贵州大学 2026-05-19 CN claimed
CN-122056343-A Jerusalem artichoke solid beverage, preparation method and application thereof in preparation of hypoglycemic drugs 吉林省健维天然生物科技有限公司 2026-05-19 CN claimed
CN-122042866-A Method for separating, detecting and identifying flavonoid component in cocoa 中国热带农业科学院香料饮料研究所 2026-05-15 CN claimed
CN-122031543-A A medicinal and edible composition for preventing and improving pulmonary nodule and pulmonary fibrosis, and its preparation method and application 南京中医药大学 2026-05-15 CN claimed
CN-122038322-A 4-Hydroxyphenylacetic acid 3-monooxygenase mutant and application thereof 南京林业大学 2026-05-15 CN claimed
US-5614501-A Compositions and methods for animal husbandry and for treating gastrointestinal disorders THE UNIVERSITY OF MONTANA (US) 1997-03-25 US claimed
EP-0719554-A1 Chondroprotective flavonoids Kureha Chemical Industry Co., Ltd. (JP) 1996-07-03 EP claimed
EP-0648488-A1 Method to alter hairgrowth and compositions therefor L'OREAL (FR) 1995-04-19 EP claimed
CN-1100633-A Chondroprotective agents KUREHA CHEMICAL IND CO LTD (JP) 1995-03-29 CN claimed
EP-0633022-A2 Chondroprotective flavones KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-11 EP claimed
EP-0316797-B1 Plants with a modified flowering colour and genetic engineering method for their production MAX PLANCK GESELLSCHAFT (DE) 1993-10-20 EP claimed
US-5141745-A Gene expression THE LUBRIZOL CORPORATION (US) 1992-08-25 US claimed
EP-0316797-A2 Plants with a modified flowering colour and genetic engineering method for their production Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1989-05-24 EP claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed