SCHEMBL39574

SCHEMBL39574

CCCC1(O)C=CC=CC1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39811 0.90 POLA1 (0.38) POLA1
SCHEMBL3796115 0.88 POLA1 (0.43) POLA1
SCHEMBL5856686 0.87 POLA1 (0.32) POLA1
SCHEMBL2957305 0.87 POLA1 (0.46) POLA1
SCHEMBL39621 0.85
SCHEMBL11490524 0.81
SCHEMBL16240897 0.81 ALDH1A1 (0.37)
SCHEMBL28737678 0.80 NPC1 (0.38)
SCHEMBL28589723 0.79
Hydrochloric Acid SCHEMBL953800 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112689501-B Make-up preparation 陶氏环球技术有限责任公司 2023-05-16 CN disclosed
CN-115227880-A Drug-coated balloon catheter for body lumens 优敦力公司 2022-10-25 CN disclosed
EP-2584896-A2 HERBICIDAL COMPOSITIONS BASF SE (DE) 2013-05-01 EP disclosed
US-20130102463-A1 Herbicidal Compositions BASF SE (DE) 2013-04-25 US disclosed
WO-2011161105-A2 HERBICIDAL COMPOSITIONS BASF SE (DE) 2011-12-29 WO disclosed
US-20080287389-A1 Nucleoside analogs in combination therapy of herpes simplex infections NOVARTIS PHARMACEUTICALS CORPORATION 2008-11-20 US disclosed
EP-1389131-A2 COMBINATIONS OF A 5HT1 RECEPTOR AGONIST WITH AN ANALGESIC, AND AN ANTI-EMETIC AND/OR A GASTROPROKINETIC AGENT GLAXO GROUP LIMITED (GB) 2004-02-18 EP disclosed
WO-2002067987-A2 COMBINATIONS OF A 5HT1 RECEPTOR AGONIST WITH AN ANALGESIC, AND AN ANTI-EMETIC AND/OR A GASTROPROKINETIC AGENT GLAXO GROUP LIMITED (GB) 2002-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102463-A1 Herbicidal Compositions PPOX, PAOX, DDT POLA1 1995/4885
US-20080287389-A1 Nucleoside analogs in combination therapy of herpes simplex infections TYMP, PNP, PAICS POLA1 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.