SCHEMBL3957808

SCHEMBL3957808

CCCCCCCCCCCC(=O)O[C@H]1[C@H](O)[C@@H](CCl)O[C@@]1(CCl)O[C@H]1O[C@H](CO)[C@H](Cl)[C@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
TLR4 O00206 6/20 0.36
PRKCA P17252 5/20 0.36
LY96 Q9Y6Y9 6/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19583432 1.00 CA2 (0.59) CA2CA9TLR4PRKCALY96
SCHEMBL19583440 1.00 CA2 (0.59) CA2CA9TLR4PRKCALY96
Sucralose SCHEMBL3953863 0.84 CA2 (0.72) CA2CA9PRKCA
SCHEMBL128339 0.81 LDHA (0.48) TLR4PRKCALY96
SCHEMBL359292 0.81 LDHA (0.48) TLR4PRKCALY96
SCHEMBL313538 0.81 LDHA (0.48) TLR4PRKCALY96
SCHEMBL39624 0.81 LDHA (0.48) TLR4PRKCALY96
SCHEMBL15435964 0.81 LDHA (0.48) TLR4PRKCALY96
SCHEMBL337163 0.81 LDHA (0.48) TLR4PRKCALY96
SCHEMBL359493 0.81 LDHA (0.48) TLR4PRKCALY96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10279050-B2 Sucrose ester based cationic gene vector and preparation method thereof DALIAN NATIONALITIES UNIVERSITY (CN) 2019-05-07 US disclosed
US-20170326255-A1 SUCROSE ESTER BASED CATIONIC GENE VECTOR AND PREPARATION METHOD THEREOF DALIAN NATIONALITIES UNIVERSITY (CN) 2017-11-16 US disclosed
US-9732108-B2 Halogenated di- and trisaccharides, pharmaceutical formulations, diagnostic kits and methods of treatment COMMON PHARMA 2017-08-15 US disclosed
EP-2077847-B1 SUCRALOSE MONOLAURATE AND SUCRALOSE MONOMYRISTATE, PHARMACEUTICAL FORMULATIONS, DIAGNOSTIC KITS AND METHODS OF TREATMENT MEMARZADEH BAHRAM (US) 2016-02-24 EP disclosed
EP-2077847-B1 SUCRALOSE MONOLAURATE AND SUCRALOSE MONOMYRISTATE, PHARMACEUTICAL FORMULATIONS, DIAGNOSTIC KITS AND METHODS OF TREATMENT MEMARZADEH BAHRAM (US) 2016-02-24 EP disclosed
US-20140065062-A1 Halogenated Di and Trisaccharides, Pharmaceutical Formulations, Diagnostic Kits and Methods of Treatment COMMON PHARMA 2014-03-06 US disclosed
US-8575333-B2 Halogenated alkyl di- and trisaccharides, pharmaceutical formulations, diagnostic kits and methods of treatment COMMON PHARMA 2013-11-05 US disclosed
US-20090318381-A1 Halogenated alkyl di-and trisaccharides, pharmaceutical formulations, diagnostic kits and methods of treatment COMMON PHARMA 2009-12-24 US disclosed
EP-2077847-A2 HALOGENATED ALKYL DI- AND TRISACCHARIDES, PHARMACEUTICAL FORMULATIONS, DIAGNOSTIC KITS AND METHODS OF TREATMENT Memarzadeh, Bahram (US) 2009-07-15 EP disclosed
US-20080171721-A1 Halogenated alkyl di- and trisaccharides, pharmaceutical formulations, diagnostic kits and methods of treatment MEMARZADEH BAHRAM 2008-07-17 US disclosed
WO-2008033543-A9 HALOGENATED ALKYL DI- AND TRISACCHARIDES, PHARMACEUTICAL FORMULATIONS, DIAGNOSTIC KITS AND METHODS OF TREATMENT MEMARZADEH BAHRAM (US) 2008-06-19 WO disclosed
WO-2008033543-A2 HALOGENATED ALKYL DI- AND TRISACCHARIDES, PHARMACEUTICAL FORMULATIONS, DIAGNOSTIC KITS AND METHODS OF TREATMENT MEMARZADEH BAHRAM (US) 2008-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318381-A1 Halogenated alkyl di-and trisaccharides, pharmaceutical formulations, diagnostic kits and methods of treatment FUCA2, UGDH, UGCG CA2 630/4885CA9 342/4885TLR4 695/4885
US-20170326255-A1 SUCROSE ESTER BASED CATIONIC GENE VECTOR AND PREPARATION METHOD THEREOF CETP, NPC1L1, LIPA CA2 3579/4885CA9 2361/4885TLR4 285/4885
US-10279050-B2 Sucrose ester based cationic gene vector and preparation method thereof CETP, NPC1L1, LIPA CA2 3579/4885CA9 2361/4885TLR4 285/4885
US-20080171721-A1 Halogenated alkyl di- and trisaccharides, pharmaceutical formulations, diagnostic kits and methods of treatment FUCA2, UGDH, UGCG CA2 630/4885CA9 342/4885TLR4 695/4885
US-20140065062-A1 Halogenated Di and Trisaccharides, Pharmaceutical Formulations, Diagnostic Kits and Methods of Treatment UGDH, UGCG, FUCA2 CA2 408/4885CA9 177/4885TLR4 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.