Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485758 | 0.96 | HTR3A (0.52) | HTR3AMEN1KMT2AHTR4 | |
| Hydrochloric Acid SCHEMBL9484526 | 0.95 | HTR3A (0.51) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL8939976 | 0.84 | HTR3A (0.49) | HTR3AMEN1KMT2AKCNH2HTR4 | |
| SCHEMBL8940239 | 0.82 | HTR3A (0.48) | HTR3AMEN1KMT2AKCNH2HTR4 | |
| SCHEMBL7271062 | 0.82 | DRD2 (0.53) | HTR3AMEN1KMT2AKCNH2HTR4 | |
| Zatosetron SCHEMBL466401 | 0.80 | HTR3A (0.51) | HTR3AMEN1KMT2AHTR4 | |
| Zatosetron SCHEMBL30949358 | 0.80 | HTR3A (0.51) | HTR3AMEN1KMT2AHTR4 | |
| Zatosetron SCHEMBL466399 | 0.80 | HTR3A (0.51) | HTR3AMEN1KMT2AHTR4 | |
| Zatosetron SCHEMBL466400 | 0.80 | HTR3A (0.51) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7270890 | 0.79 | HTR3A (0.48) | HTR3AMEN1KMT2AKCNH2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | claimed |
| JP-5070456-A | — | — | None | — | — | JP | disclosed |
| EP-1741430-B1 | REMEDY FOR PSYCHONEUROTIC DISEASES | UNIV CHIBA NAT UNIV CORP (JP) | 2009-07-15 | — | — | EP | disclosed |
| JP-H0570456-A | BENZOXAZINE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1993-03-23 | — | — | JP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |