Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31183707 | 0.80 | POLB (0.43) | POLBMAPTIDO1LMNASMN1; SMN2 | |
| SCHEMBL1600326 | 0.79 | IDO1 (0.38) | IDO1HRH4CYP3A4CYP2D6 | |
| SCHEMBL3952559 | 0.76 | AR (0.39) | IDO1CYP2D6 | |
| SCHEMBL3954839 | 0.75 | LMNA (0.39) | POLBLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL957709 | 0.72 | PPARA (0.41) | POLBMAPTIDO1LMNASMN1; SMN2 | |
| SCHEMBL9952943 | 0.70 | POLB (0.39) | POLBMAPTIDO1LMNASMN1; SMN2 | |
| SCHEMBL1600943 | 0.70 | MEN1 (0.40) | IDO1 | |
| SCHEMBL1600954 | 0.69 | SLC6A4 (0.34) | IDO1 | |
| SCHEMBL3951900 | 0.69 | PDE2A (0.34) | IDO1 | |
| SCHEMBL3683402 | 0.69 | POLB (0.38) | POLBMAPTIDO1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027785-A2 | 1, 3-OXAZOLE DERIVATIVES AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2009-03-05 | — | — | WO | disclosed |