Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464988 | 0.73 | CNR2 (0.70) | CNR2MEN1KMT2AIDH1 | |
| SCHEMBL1465790 | 0.71 | ABL1 (0.55) | MAPTMEN1KMT2AKDM1ANPC1 | |
| SCHEMBL1463644 | 0.66 | ABL1 (0.53) | CNR2MAPTMEN1KMT2AKDM1A | |
| SCHEMBL1466154 | 0.66 | MEN1 (0.53) | ALDH1A1MAPTMEN1KMT2AKDM1A | |
| SCHEMBL1465504 | 0.66 | CNR2 (0.58) | CNR2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL1464344 | 0.64 | CNR2 (1.00) | CNR2MAPTIDH1 | |
| SCHEMBL12635885 | 0.64 | KDM1A (0.52) | ALOX5ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1464367 | 0.63 | CNR2 (0.74) | CNR2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1465056 | 0.63 | FFAR2 (0.49) | CNR2 | |
| SCHEMBL13021195 | 0.62 | RAB9A (0.59) | ALOX5L3MBTL1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |