Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446594 | 0.85 | ALDH1A1 (0.52) | CYP2A6CYP1A2AGXTTDP1GAA | |
| SCHEMBL11040449 | 0.82 | ESR1 (0.55) | CYP2A6CYP1A2AGXTKDM4ECA1 | |
| SCHEMBL20710755 | 0.82 | CYP2A6 (0.48) | CYP2A6CYP1A2AGXTTDP1KDM4E | |
| SCHEMBL8397144 | 0.81 | CYP2A6 (0.52) | CYP2A6CYP1A2AGXTTDP1KDM4E | |
| SCHEMBL10946368 | 0.81 | CYP2A6 (0.52) | CYP2A6CYP1A2AGXTTDP1KDM4E | |
| SCHEMBL4238279 | 0.81 | CYP1A2 (0.52) | CYP2A6CYP1A2AGXTTDP1KDM4E | |
| SCHEMBL11587475 | 0.81 | CYP1A2 (0.52) | CYP2A6CYP1A2AGXTTDP1KDM4E | |
| SCHEMBL27619363 | 0.81 | CYP2A6 (0.52) | CYP2A6CYP1A2AGXTTDP1KDM4E | |
| SCHEMBL13839484 | 0.80 | KMT2A (0.42) | CYP2A6CYP1A2TDP1GAARCE1 | |
| SCHEMBL8487523 | 0.80 | NCOA1 (0.42) | CYP2A6CYP1A2AGXTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220884-B2 | Hydroaminomethylation of olefins | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2007-05-22 | — | — | US | claimed |
| EP-1713757-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2006-10-25 | — | — | EP | claimed |
| US-20050215825-A1 | Hydroaminomethylation of olefins | UNION CARBIDE CORPORATION | 2005-09-29 | — | — | US | claimed |
| WO-2005077884-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-08-25 | — | — | WO | claimed |
| US-3966697-A | CATALYST OF COBALT COMPOUND, ORGANOALUMINUM HALIDE, PHOSPHITE, H-ACIDIC COMPOUND | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
| JP-4288033-A | — | — | None | — | — | JP | disclosed |
| US-20230257619-A1 | Curing of reaction resins using unsaturated peroxides as initiators and organic phosphites as accelerators | RÖHM GMBH (DE) | 2023-08-17 | — | — | US | disclosed |
| WO-2020124996-A1 | METHOD FOR STABILIZING PHOSPHITE LIGAND AND APPLICATION THEREOF | 浙江新和成股份有限公司 | 2020-06-25 | — | — | WO | disclosed |
| US-20090312450-A1 | POLYURETHANES MADE FROM HYDROXYL-CONTAINING FATTY ACID AMIDES | DOW GLOBAL TECHNOLOGIES, INC. | 2009-12-17 | — | — | US | disclosed |
| EP-1913049-B1 | POLYURETHANES MADE FROM HYDROXYL-CONTAINING FATTY ACID AMIDES | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-07-22 | — | — | EP | disclosed |
| US-7220884-B2 | Hydroaminomethylation of olefins | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2007-05-22 | — | — | US | disclosed |
| EP-1713757-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2006-10-25 | — | — | EP | disclosed |
| US-4202844-A | OXIDATION OF ORGANIC PHOSPHITES WITH NITROGEN DIOXIDE AS CATALYST | TENNECO CHEMICALS, INC. (US) | 1980-05-13 | — | — | US | disclosed |
| US-4202843-A | Process for the production of organic phosphates by nitric acid oxidation of organic phosphites | TENNECO CHEMICALS, INC. (US) | 1980-05-13 | — | — | US | disclosed |
| US-4187385-A | TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE | MITSUI TOATSU CHEMICAL, INC. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4125540-A | WITH ORGANO-PHOSPHORUS COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1978-11-14 | — | — | US | disclosed |
| US-4087411-A | TRIOXANE, BORON FLUORIDE-TYPE CATALYST | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1978-05-02 | — | — | US | disclosed |
| US-4067903-A | Manufacture of arylamines | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |
| US-3966697-A | CATALYST OF COBALT COMPOUND, ORGANOALUMINUM HALIDE, PHOSPHITE, H-ACIDIC COMPOUND | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215825-A1 | Hydroaminomethylation of olefins | HRH2, HRH4, HRH1 | CYP2A6 146/4885CYP1A2 204/4885AGXT 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.