Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955111 | 0.92 | ADORA3 (0.41) | CNR2YTHDC1ADORA3 | |
| SCHEMBL3958919 | 0.88 | ADORA2A (0.46) | ADORA2AADORA3 | |
| SCHEMBL3963292 | 0.88 | PIK3CD (0.44) | ADORA2AADORA3 | |
| SCHEMBL3958684 | 0.88 | PDE8A (0.43) | YTHDC1ADORA3 | |
| SCHEMBL3961113 | 0.88 | PDE4A (0.49) | ADORA2A | |
| SCHEMBL7208530 | 0.87 | PDE4A (0.55) | ADORA2AADORA3 | |
| SCHEMBL3954593 | 0.86 | CNR2 (0.43) | CNR2ADORA3 | |
| SCHEMBL3955318 | 0.86 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL3964379 | 0.85 | GAA (0.45) | CNR2ADORA3 | |
| SCHEMBL7205445 | 0.84 | PDE4A (0.54) | ADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |