Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.37 |
| ▸ | HTR7 | P34969 | 8/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960852 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DRD4HTR7 | |
| SCHEMBL3958641 | 0.83 | HTR7 (0.49) | SLC6A2SLC6A4SLC6A3DRD4HTR7 | |
| SCHEMBL3957776 | 0.83 | HTR7 (0.49) | SLC6A2SLC6A4SLC6A3DRD4HTR7 | |
| SCHEMBL3957782 | 0.83 | HTR7 (0.49) | SLC6A2SLC6A4SLC6A3DRD4HTR7 | |
| SCHEMBL11882731 | 0.78 | DRD3 (0.52) | DRD4HTR7DRD2DRD3HTR1A | |
| SCHEMBL3953411 | 0.76 | KDM4E (0.38) | SLC6A2SLC6A4SLC6A3DRD4HTR7 | |
| SCHEMBL3953405 | 0.76 | KDM4E (0.38) | SLC6A2SLC6A4SLC6A3DRD4HTR7 | |
| SCHEMBL3959928 | 0.74 | DRD4 (0.39) | SLC6A4DRD4HTR7DRD2DRD3 | |
| SCHEMBL3959934 | 0.74 | DRD4 (0.39) | SLC6A4DRD4HTR7DRD2DRD3 | |
| Oxalic Acid SCHEMBL3966802 | 0.74 | KDM4E (0.37) | SLC6A2SLC6A4SLC6A3DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544685-B2 | 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | disclosed |
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | HTR2C, HTR2A, HTR5A | SLC6A2 48/4885SLC6A4 28/4885SLC6A3 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.