SCHEMBL3961052

SCHEMBL3961052

CCO[Si](CN1C(=O)C=CC1=O)(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.48
ALDH1A1 P00352 3/20 0.48
BLM P54132 2/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
GMNN O75496 1/20 0.48
THPO P40225 1/20 0.48
PMP22 Q01453 1/20 0.48
GSK3A P49840 5/20 0.44
GSK3B P49841 5/20 0.44
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
WRN Q14191 1/20 0.41
HIF1A Q16665 1/20 0.41
FAAH O00519 5/20 0.39
PTGS1 P23219 4/20 0.39
PTGS2 P35354 4/20 0.39
HSP90AA1 P07900 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3963640 0.82 MGLL (0.46) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL3963636 0.78 MGLL (0.46) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL638714 0.77 MGLL (0.52) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL28348211 0.74 MGLL (0.58) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL15726727 0.73
SCHEMBL2504222 0.71 ALDH1A1 (0.32) ALDH1A1
SCHEMBL8734103 0.70 MGLL (0.52) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL3679923 0.70 MGLL (0.41) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL28365540 0.69 MGLL (0.56) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL14571854 0.68 MGLL (0.50) MGLLALDH1A1BLMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009147024-A1 BINDERS BASED ON POLYMERS CONTAINING ALPHA-SILANE GROUPS WACKER CHEMIE AG (DE) 2009-12-10 WO disclosed
WO-2009033908-A2 MOISTURE CROSS-LINKABLE POLYMERS BASED ON ALPHA-HETEROATOM SUBSTITUTED SILANES WACKER CHEMIE AG (DE) 2009-03-19 WO disclosed