Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342500 | 0.86 | PRCP (0.68) | CTRB1PRCPITGB3ITGA2BKMT2A | |
| SCHEMBL22127840 | 0.86 | ITGB3 (0.54) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL22127953 | 0.86 | ITGB3 (0.54) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL22127842 | 0.86 | ITGB3 (0.54) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL10909410 | 0.86 | ITGB3 (0.56) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL10791840 | 0.84 | ITGB3 (0.53) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL22128002 | 0.84 | ITGB3 (0.57) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL22128003 | 0.84 | ITGB3 (0.57) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL22128005 | 0.84 | ITGB3 (0.57) | CTRB1PRCPITGB3ITGA2BCMA1 | |
| SCHEMBL22127939 | 0.84 | ITGB3 (0.48) | CTRB1PRCPITGB3ITGA2BCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866291-B1 | ANTIBACTERIAL AMIDE MACROCYCLES VI | AICURIS GMBH & CO KG (DE) | 2009-07-15 | — | — | EP | disclosed |
| US-20080300231-A1 | Antibacterial amide macrocycles VI | BAYER HEALTHCARE AG (DE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300231-A1 | Antibacterial amide macrocycles VI | AADAC, AAAS, NOD2 | CTRB1 731/4885PRCP 1420/4885ITGB3 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.