Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957829 | 1.00 | CCKBR (0.40) | CCKBRPAX8TDO2BCHEHRH2 | |
| SCHEMBL1688324 | 1.00 | CCKBR (0.40) | CCKBRPAX8TDO2BCHEHRH2 | |
| SCHEMBL31366241 | 0.89 | CCKBR (0.39) | CCKBRPAX8BCHEOPRM1 | |
| SCHEMBL14610590 | 0.89 | CCKBR (0.39) | CCKBRPAX8BCHEOPRM1 | |
| SCHEMBL550107 | 0.85 | CCKBR (0.42) | CCKBRPAX8HRH2OPRM1HTR2B | |
| SCHEMBL11851728 | 0.81 | CCKBR (0.40) | CCKBRPAX8BCHEHRH2OPRM1 | |
| SCHEMBL11473137 | 0.81 | IDO1 (0.45) | CCKBR | |
| SCHEMBL29558888 | 0.81 | IDO1 (0.45) | CCKBR | |
| SCHEMBL5543945 | 0.81 | CCKBR (0.40) | CCKBRPAX8BCHEHRH2OPRM1 | |
| SCHEMBL8261364 | 0.81 | HTR5A (0.41) | CCKBRBCHEHRH2OPRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544685-B2 | 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | disclosed |
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | HTR2C, HTR2A, HTR5A | CCKBR 162/4885PAX8 3199/4885TDO2 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.