Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961462 | 1.00 | KCNA5 (0.42) | KCNA5CPB1PSEN1PSEN2APH1B | |
| SCHEMBL19333763 | 1.00 | KCNA5 (0.42) | KCNA5CPB1PSEN1PSEN2APH1B | |
| SCHEMBL3961464 | 1.00 | KCNA5 (0.42) | KCNA5CPB1PSEN1PSEN2APH1B | |
| SCHEMBL3961461 | 1.00 | KCNA5 (0.42) | KCNA5CPB1PSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL6234960 | 0.99 | TSHR (0.41) | KCNA5CPB1PSEN1PSEN2APH1B | |
| SCHEMBL198727 | 0.86 | TACR1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19333652 | 0.86 | TACR1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6744373 | 0.82 | KLK7 (0.42) | BCHETACR1TSHRACHE | |
| SCHEMBL19225926 | 0.81 | TSHR (0.48) | CPB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27553719 | 0.80 | ALDH1A1 (0.39) | BCHETACR1ALDH1A1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038411-A2 | BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |