Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893820 | 0.80 | KMT2A (0.67) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL4249926 | 0.78 | CASR (0.52) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL11673049 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL9119369 | 0.76 | KMT2A (0.70) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL9781400 | 0.76 | MEN1 (0.70) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL9119354 | 0.76 | KMT2A (0.70) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL8802147 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1POLBMAPK1 | |
| SCHEMBL9781310 | 0.75 | MEN1 (0.68) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL16764313 | 0.75 | MEN1 (0.60) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL4689993 | 0.75 | MEN1 (0.68) | MEN1KMT2AALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784407-A4 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2009-02-11 | — | — | EP | disclosed |
| EP-1784407-A1 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025634-A1 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |