Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416033 | 0.84 | CASR (0.57) | CASRALDH1A1HTTSMN1; SMN2TAAR1 | |
| SCHEMBL2954251 | 0.81 | CASR (0.60) | CASRALDH1A1HTTSMN1; SMN2TAAR1 | |
| SCHEMBL3961688 | 0.78 | MEN1 (0.57) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL5433128 | 0.78 | CASR (0.50) | CASRALDH1A1HTTSMN1; SMN2TAAR1 | |
| SCHEMBL3966026 | 0.77 | SIGMAR1 (0.53) | CASRALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL3099211 | 0.77 | SIGMAR1 (0.53) | CASRALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL5270682 | 0.76 | MEN1 (0.75) | CASRALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12154819 | 0.76 | MEN1 (0.75) | CASRALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12472188 | 0.76 | CASR (0.55) | CASRALDH1A1HTTSMN1; SMN2TAAR1 | |
| SCHEMBL27614960 | 0.76 | DNM1 (0.60) | ALDH1A1HTTSMN1; SMN2TAAR1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784407-A4 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2009-02-11 | — | — | EP | disclosed |
| EP-1784407-A1 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025634-A1 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |