Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958768 | 0.89 | APP (0.40) | APPIKBKBCHUKDHODHC5AR1 | |
| SCHEMBL3958453 | 0.89 | APP (0.45) | APPIKBKBCHUKC5AR1CNR2 | |
| SCHEMBL1201622 | 0.83 | APP (0.45) | APPPTGDR2IKBKBCHUKFFAR1 | |
| SCHEMBL3961706 | 0.82 | APP (0.39) | APPIKBKBCHUKFFAR4DHODH | |
| SCHEMBL8031372 | 0.80 | APP (0.49) | APPPTGDR2FFAR4DHODHFFAR1 | |
| SCHEMBL3659452 | 0.79 | APP (0.54) | APPPTGDR2FFAR4CNR2 | |
| SCHEMBL15494189 | 0.79 | APP (0.47) | APPPTGDR2FFAR4DHODHPPARD | |
| SCHEMBL15111458 | 0.78 | APP (0.53) | APPFFAR4DHODHCTSSCTSK | |
| SCHEMBL27820362 | 0.78 | APP (0.47) | APPCTSSCTSKCNR2PDE10A | |
| SCHEMBL27799350 | 0.78 | APP (0.49) | APPCTSSCTSKPTGS2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036428-A2 | 1,3,4-TRISUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |