Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494189 | 0.90 | APP (0.47) | APPFFAR4KDM4CCNR2DHODH | |
| SCHEMBL3659869 | 0.89 | APP (0.62) | APPFFAR4PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL3712241 | 0.84 | APP (0.63) | APPFFAR4KDM4CCNR2DHODH | |
| SCHEMBL15111461 | 0.81 | APP (0.42) | APPFFAR4CNR2ACACBPDE4A | |
| SCHEMBL3659452 | 0.81 | APP (0.54) | APPFFAR4CNR2ACACBPTGDR2 | |
| SCHEMBL3961703 | 0.80 | APP (0.41) | APPFFAR4KDM4CCNR2DHODH | |
| SCHEMBL1203108 | 0.79 | APP (0.56) | APPFFAR4KDM4CCNR2ACACB | |
| SCHEMBL13968158 | 0.78 | APP (0.60) | APPKEAP1NFE2L2CNR2PDE4A | |
| SCHEMBL16488452 | 0.78 | APP (0.51) | APPDHODHPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL3961706 | 0.78 | APP (0.39) | APPFFAR4KDM4CCNR2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086277-A1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |