Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167940 | 0.88 | LRRK2 (0.47) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL2167339 | 0.88 | LRRK2 (0.47) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL27563218 | 0.88 | LRRK2 (0.47) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL8321821 | 0.85 | CCR5 (0.54) | LMNAUSP2CCR5MEN1KMT2A | |
| SCHEMBL6497698 | 0.85 | LMNA (0.53) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL6330912 | 0.85 | MRGPRX4 (0.48) | ALDH1A1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL17705192 | 0.84 | CCR5 (0.53) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL17705196 | 0.80 | CCR5 (0.59) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL17705193 | 0.79 | CCR5 (0.52) | LMNAUSP2CCR5LRRK2ALDH1A1 | |
| SCHEMBL16293408 | 0.79 | CCR5 (0.52) | LMNAUSP2CCR5LRRK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037569-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF FESOTERODINE | ACTAVIS GROUP PTC EHF (IS) | 2009-03-26 | — | — | WO | disclosed |