Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711156 | 0.77 | NOS3 (0.48) | MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL2176589 | 0.76 | MEN1 (0.33) | MEN1KMT2ARAB9A | |
| SCHEMBL3971495 | 0.74 | NOS3 (0.37) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL15053158 | 0.74 | S1PR1 (0.37) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL27621066 | 0.72 | — | — | |
| SCHEMBL6629976 | 0.72 | — | — | |
| SCHEMBL7842711 | 0.71 | LMNA (0.41) | — | |
| SCHEMBL7919664 | 0.69 | HTT (0.31) | ALOX15ALDH1A1KDM4EGAA | |
| SCHEMBL11712416 | 0.68 | — | — | |
| SCHEMBL1765148 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078721-B1 | Thieno-pyrimidine compounds having fungicidal activity | DOW AGROSCIENCES LLC (US) | 2014-01-22 | — | — | EP | disclosed |
| WO-2013105753-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AND METHODS FOR PREPARING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2013-07-18 | — | — | WO | disclosed |
| WO-2013105753-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AND METHODS FOR PREPARING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2013-07-18 | — | — | WO | disclosed |
| EP-2078721-A2 | Thieno-pyrimidime compounds having fungicidal activity | Dow AgroSciences LLC (US) | 2009-07-15 | — | — | EP | disclosed |
| US-7531482-B2 | Thieno-pyrimidine compounds having fungicidal activity | DOW AGROSCIENCES LLC (US) | 2009-05-12 | — | — | US | disclosed |
| EP-1937691-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2008-07-02 | — | — | EP | disclosed |
| US-20070093498-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2007-04-26 | — | — | US | disclosed |
| WO-2007046809-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093498-A1 | Thieno-pyrimidine compounds having fungicidal activity | TYMP, DPM1, TYMS | CYP3A4 138/4885CHRM1 3508/4885ALOX15 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.