Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hexadecylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11466733 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL11462091 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Decylamine SCHEMBL989202 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Octadecylamine SCHEMBL9460974 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetradecylamine SCHEMBL238293 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Pentadecylamine SCHEMBL11453009 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL474302 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL11455986 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL11471709 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL10812415 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117185937-A | Method for improving quality of 2, 6-dichloro-4-trifluoromethyl aniline | 江苏优普生物化学科技股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-112778119-A | Green aqueous phase solvent-free high-purity synthesis method of palmitoylethanolamide | 杭州洁汉化工有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-111759774-A | Whitening anti-wrinkle essence | 刘婷 | 2020-10-13 | — | — | CN | claimed |
| CN-111468151-A | Mo with lamellar structure2C cocatalyst, preparation and application | 宁夏大学 | 2020-07-31 | — | — | CN | claimed |
| CN-106714792-A | Mixtures of fatty acids and palmitoylethanolamide for the treatment of inflammatory and allergic pathologies | R·米利亚乔 | 2017-05-24 | — | — | CN | claimed |
| CN-118291108-A | Nanometer surfactant and preparation method and application thereof | 宁波锋成纳米科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-114405483-B | Porous cellulose microsphere adsorbent with core-shell structure, preparation method and application | 健帆生物科技集团股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117210042-A | High-absorbance singular-point black nanoscale conductive oil paint and preparation method thereof | 肇庆市创微纳米科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117185937-A | Method for improving quality of 2, 6-dichloro-4-trifluoromethyl aniline | 江苏优普生物化学科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117043200-A | Oil-resistant compound containing hydrogen bond site | 大金工业株式会社 | 2023-11-10 | — | — | CN | disclosed |
| CN-116715275-A | Surface hydrophobic modification method of ferroferric oxide magnetic nanoparticle | 南昌航空大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-116284964-A | Cellulose microsphere adsorbent and preparation method thereof | 吉林大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-110372467-A | A method of the hydrocracking C10 aromartic based on extracting rectifying extracts durol | 鹏辰新材料科技股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105585855-B | A kind of organic montmorillonite flame-retardant pitch and preparation method thereof | 中国石油化工股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105585279-B | A kind of modified asphalt mixture and preparation method thereof | 中国石油化工股份有限公司 | 2018-03-16 | — | — | CN | disclosed |
| CN-107722352-A | A kind of chain alkyl amino-functionalization graphene and preparation method thereof | 浙江山峪科技股份有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-105585736-B | A kind of road asphalt modifier and preparation method thereof | 中国石油化工股份有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-106138022-A | Compositions containing ultra micro granulation palmidrol | 晶源集团有限公司 | 2016-11-23 | — | — | CN | disclosed |
| WO-2009029979-A1 | COATING COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | DEAKIN UNIVERSITY (AU) | 2009-03-12 | — | — | WO | disclosed |
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |