Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11466733 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL11462091 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Decylamine SCHEMBL989202 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Octadecylamine SCHEMBL9460974 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetradecylamine SCHEMBL238293 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Pentadecylamine SCHEMBL11453009 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Hexadecylamine SCHEMBL3962485 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL11455986 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL11471709 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL10812415 | 1.00 | DNM1 (0.81) | DNM1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260559-B2 | Processes for the preparation of rheology modifiers | ELEMENTIS SPECIALTIES, INC. (US) | 2016-02-16 | — | — | US | claimed |
| EP-2759555-B1 | Processes for the preparation of rheoloy modifiers | ELEMENTIS SPECIALTIES INC (US) | 2016-02-03 | — | — | EP | claimed |
| EP-2759555-A1 | Processes for the preparation of rheoloy modifiers | Elementis Specialties, Inc. (US) | 2014-07-30 | — | — | EP | claimed |
| US-20140135468-A1 | PROCESSES FOR THE PREPARATION OF RHEOLOGY MODIFIERS | ELEMENTIS SPECIALTIES, INC. | 2014-05-15 | — | — | US | claimed |
| CN-116332234-A | Preparation method and application of transition metal chalcogenides spindle-shaped nanotubes | 南京邮电大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-110102288-B | Metal pillared modified layered manganese Birnessite and preparation and application thereof | 北京化工大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-105885516-B | Acid suppressible rheology modifiers stabilized by phosphate ester surfactants | 罗门哈斯公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-110102288-A | A kind of pillared modified layered manganese Birnessite of metal and its preparation and application | 北京化工大学 | 2019-08-09 | — | — | CN | disclosed |
| EP-3056550-B1 | ACID SUPPRESSIBLE RHEOLOGY MODIFIER STABILIZED WITH PHOSPHORIC ACID ESTER SURFACTANT | ROHM & HAAS (US) | 2018-07-04 | — | — | EP | disclosed |
| US-9790345-B2 | Acid suppressible rheology modifier stabilized with phosphoric acid ester surfactant | ROHM AND HAAS COMPANY (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160237247-A1 | ACID SUPPRESSIBLE RHEOLOGY MODIFIER STABILIZED WITH PHOSPHORIC ACID ESTER SURFACTANT | ROHM AND HAAS COMPANY | 2016-08-18 | — | — | US | disclosed |
| EP-3056550-A1 | ACID SUPPRESSIBLE RHEOLOGY MODIFIER STABILIZED WITH PHOSPHORIC ACID ESTER SURFACTANT | ROHM AND HAAS COMPANY (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20080234411-A1 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY | 2008-09-25 | — | — | US | disclosed |
| EP-1972665-A2 | Thickener composition and method for thickening aqueous systems | Rohm and Haas Company (US) | 2008-09-24 | — | — | EP | disclosed |
| US-20060005464-A1 | Alkyl ethanolamine and biocide combination for hydrocarbon based fuels | TAMINCO (BE) | 2006-01-12 | — | — | US | disclosed |
| US-20060005463-A1 | Alkyl ethanolamine and biocide combination for hydrocarbon based fuels | ARKEMA INC | 2006-01-12 | — | — | US | disclosed |
| US-20050288388-A1 | Compositions providing physical biocide synergist activity in paints, coatings, sealants and adhesives during storage | TAMINCO NV (BE) | 2005-12-29 | — | — | US | disclosed |
| EP-1362897-A2 | N-ethanolamines for the stabilization of latex compositions | Atofina Chemicals, Inc. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20030209165-A1 | Compositions providing physical biocide synergist activity in paints, coatings, sealants and adhesives during storage | ARKEMA INC. | 2003-11-13 | — | — | US | disclosed |
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |