Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464561 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL3963509 | 0.88 | AGTR1 (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL1465574 | 0.84 | CNR2 (0.56) | CNR2 | |
| SCHEMBL1463755 | 0.80 | AGTR1 (0.62) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL1463644 | 0.77 | ABL1 (0.53) | SMN1; SMN2KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL1466154 | 0.75 | MEN1 (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL1464642 | 0.75 | CNR2 (0.54) | CNR2 | |
| SCHEMBL3965000 | 0.74 | CNR2 (0.50) | CNR2LMNA | |
| SCHEMBL1464917 | 0.72 | MEN1 (0.64) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL1621153 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |