Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428688 | 1.00 | LMNA (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL15766523 | 1.00 | LMNA (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL11738774 | 1.00 | LMNA (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL524256 | 0.98 | LMNA (0.73) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL8154526 | 0.93 | LMNA (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL15154872 | 0.88 | LMNA (0.77) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL3135517 | 0.88 | LMNA (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL3665313 | 0.87 | KMT2A (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL168816 | 0.87 | KMT2A (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL18141371 | 0.87 | KMT2A (0.74) | LMNAMAPTCYP3A4MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221921-A1 | SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND | RNS CO.,LTD. (KR) | 2016-08-04 | — | — | US | disclosed |
| US-7566737-B2 | Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
| CN-85101534-A | The method of curable synthetic resin composition and manufacturing multipolymer | — | 1987-01-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | LMNA 1551/4885MAPT 133/4885CYP3A4 3088/4885 |
| US-20160221921-A1 | SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND | H1-10, HCN1, HCN4 | LMNA 494/4885MAPT 4627/4885CYP3A4 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.