Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963636 | 0.80 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL3963640 | 0.79 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL8734103 | 0.77 | MGLL (0.52) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL2499398 | 0.70 | TP53 (0.31) | TP53SMN1; SMN2 | |
| SCHEMBL277926 | 0.69 | MGLL (0.55) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL6480093 | 0.68 | MGLL (0.48) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL19089770 | 0.68 | MGLL (0.54) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL3961052 | 0.68 | MGLL (0.48) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL296687 | 0.65 | MGLL (0.56) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL3482689 | 0.65 | MGLL (0.38) | MGLLALDH1A1BLMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147024-A1 | BINDERS BASED ON POLYMERS CONTAINING ALPHA-SILANE GROUPS | WACKER CHEMIE AG (DE) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009033908-A2 | MOISTURE CROSS-LINKABLE POLYMERS BASED ON ALPHA-HETEROATOM SUBSTITUTED SILANES | WACKER CHEMIE AG (DE) | 2009-03-19 | — | — | WO | disclosed |