Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161816 | 0.87 | NAMPT (0.38) | SLC18A3HRH3PRCPNAMPTACHE | |
| SCHEMBL3962898 | 0.77 | HRH3 (0.38) | SLC18A3HRH3PRCPNAMPTACHE | |
| SCHEMBL3962892 | 0.77 | HRH3 (0.38) | SLC18A3HRH3PRCPNAMPTACHE | |
| SCHEMBL3960490 | 0.74 | SMYD3 (0.47) | LMNA | |
| SCHEMBL6597727 | 0.73 | HRH3 (0.40) | SLC18A3HRH3PRCPNAMPTACHE | |
| SCHEMBL4706551 | 0.66 | JAK2 (0.48) | HRH3LMNA | |
| SCHEMBL3964152 | 0.65 | SMYD3 (0.49) | LMNA | |
| Hydrochloric Acid SCHEMBL9811414 | 0.64 | SIGMAR1 (0.56) | SLC18A3HRH3PRCPLMNA | |
| SCHEMBL25698065 | 0.63 | HRH3 (0.48) | SLC18A3HRH3ACHELMNA | |
| SCHEMBL31688703 | 0.62 | SLC18A3 (0.58) | SLC18A3PRCPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-6344449-B1 | HEADACHE AND MORPHINE DEPENDENCE | DR. KARL THOMAE GMBH (DE) | 2002-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | SLC18A3 129/4885HRH3 14/4885PRCP 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.