SCHEMBL396292

SCHEMBL396292

C=C(C)C(=O)OC[Si](OC)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 3/20 0.40
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18965500 0.96 TSHR (0.40) ALDH1A1TSHRTHRB
SCHEMBL396761 0.91 TSHR (0.48) ALDH1A1TSHRTHRB
SCHEMBL396532 0.89 TSHR (0.47) ALDH1A1TSHRTHRB
SCHEMBL82401 0.87 TSHR (0.47) ALDH1A1TSHRTHRB
SCHEMBL14010553 0.86 TSHR (0.40) ALDH1A1TSHRTHRB
SCHEMBL9714988 0.84 TSHR (0.43) ALDH1A1TSHRTHRB
SCHEMBL17236328 0.84 TSHR (0.43) ALDH1A1TSHRTHRB
SCHEMBL17229938 0.84 THRB (0.41) ALDH1A1TSHRTHRB
SCHEMBL395895 0.82 TSHR (0.40) ALDH1A1TSHRTHRB
SCHEMBL28371093 0.82 TSHR (0.40) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110697-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-02-07 US disclosed
US-8101789-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-01-24 US disclosed
EP-2125833-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
EP-2125834-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
US-20100041909-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-18 US disclosed
US-20100029972-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-04 US disclosed