Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 12/20 | 0.77 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.65 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.65 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.64 |
| ▸ | GPX4 | P36969 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16887951 | 0.87 | CACNA1G (0.72) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3964691 | 0.86 | CACNA1G (0.69) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3958369 | 0.85 | CACNA1G (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3954648 | 0.85 | CACNA1G (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL7663999 | 0.83 | CNR1 (0.73) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3954671 | 0.82 | CACNA1G (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5370723 | 0.82 | CACNA1G (0.65) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5268519 | 0.79 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5266301 | 0.79 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL4179713 | 0.79 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035307-A2 | NOVEL COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME FOR INHIBITING PAIN | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2009-03-19 | — | — | WO | disclosed |