SCHEMBL396300

SCHEMBL396300

C=C(Cc1ccccc1S(=O)(=O)NCC)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.47
CA9 Q16790 6/20 0.47
ALDH1A1 P00352 5/20 0.41
LMNA P02545 2/20 0.41
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
KMT2A Q03164 1/20 0.38
MMP2 P08253 4/20 0.38
MMP8 P22894 4/20 0.38
MMP13 P45452 4/20 0.38
MMP12 P39900 3/20 0.38
MMP14 P50281 3/20 0.38
MMP16 P51512 3/20 0.38
MMP1 P03956 3/20 0.38
MMP9 P14780 3/20 0.38
MMP3 P08254 2/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396805 0.89 CA12 (0.58) CA12CA9ALDH1A1LMNACA1
SCHEMBL393613 0.87 CYP1A2 (0.44) CA12CA9MMP2MMP8MMP13
SCHEMBL397450 0.87 CA12 (0.60) CA12CA9ALDH1A1LMNAKMT2A
SCHEMBL397624 0.81 ALDH1A1 (0.47) CA12CA9ALDH1A1KMT2AMMP2
SCHEMBL13469361 0.78 CA12 (0.47) CA12CA9ALDH1A1LMNAALOX5AP
SCHEMBL392892 0.77 CA1 (0.44) CA12CA9MMP2MMP8MMP13
SCHEMBL397253 0.77 PTGDR2 (0.46) ALDH1A1LMNAMMP2MMP8MMP13
SCHEMBL7336703 0.74 AKR1B1 (0.41) ALDH1A1
SCHEMBL8746636 0.74 AKR1B1 (0.46) ALDH1A1LMNAKMT2APOLB
SCHEMBL396597 0.74 ALDH1A1 (0.60) ALDH1A1LMNAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed