SCHEMBL397450

SCHEMBL397450

C=C(Cc1ccccc1S(=O)(=O)NCCCC)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.60
CA9 Q16790 3/20 0.60
RECQL P46063 1/20 0.48
ALDH1A1 P00352 7/20 0.46
TSHR P16473 2/20 0.42
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C19 P33261 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
EPHX2 P34913 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 3/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396805 0.92 CA12 (0.58) CA12CA9RECQLALDH1A1L3MBTL1
SCHEMBL396300 0.87 CA12 (0.47) CA12CA9ALDH1A1KMT2ALMNA
SCHEMBL393613 0.82 CYP1A2 (0.44) CA12CA9TSHRCYP1A2
SCHEMBL9462811 0.80 CA12 (0.63) CA12CA9RECQLALDH1A1TSHR
SCHEMBL5189488 0.78 CA12 (0.60) CA12CA9RECQLALDH1A1TSHR
SCHEMBL397624 0.77 ALDH1A1 (0.47) CA12CA9RECQLALDH1A1TSHR
SCHEMBL397044 0.76 LMNA (0.56) CA12CA9ALDH1A1TSHRKMT2A
SCHEMBL397310 0.75 CA12 (0.54) CA12CA9RECQLALDH1A1TSHR
SCHEMBL397008 0.75 ALDH1A1 (0.49) CA12CA9ALDH1A1TSHRCYP2C19
SCHEMBL28318605 0.75 RECQL (0.70) CA12CA9RECQLALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed