Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 7/20 | 0.41 |
| ▸ | KHK | P50053 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3542731 | 0.99 | CSF1R (0.55) | CSF1RGAAMEN1USP2KMT2A | |
| SCHEMBL3963228 | 0.83 | CSF1R (0.56) | CSF1RGAAQDPRHTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL3542729 | 0.82 | CSF1R (0.55) | CSF1RGAAQDPRHTR2CSIGMAR1 | |
| SCHEMBL27691386 | 0.74 | GAA (0.46) | CSF1RGAAMEN1USP2KMT2A | |
| SCHEMBL20847821 | 0.73 | HTR2C (0.57) | QDPRHTR2CKHKSIGMAR1ALDH1A1 | |
| SCHEMBL13439367 | 0.73 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405655 | 0.72 | CSF1R (0.75) | CSF1RPOLB | |
| SCHEMBL3958578 | 0.71 | GAA (0.55) | CSF1RGAAMEN1USP2KMT2A | |
| SCHEMBL12479331 | 0.71 | QDPR (0.72) | QDPRHTR2CKHKSIGMAR1ALDH1A1 | |
| SCHEMBL3542138 | 0.70 | CSF1R (0.52) | CSF1RGAAMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | claimed |