Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6130294 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6653675 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8350047 | 0.81 | TP53 (0.52) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL84733 | 0.80 | ARG1 (0.48) | ALDH1A1CYP1A2CYP2D6CYP3A4MEN1 | |
| SCHEMBL14465086 | 0.79 | TSHR (0.52) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL27786790 | 0.78 | ARG1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP3A4MEN1 | |
| Bromide SCHEMBL28351801 | 0.78 | ARG1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL16280191 | 0.77 | TSHR (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29606739 | 0.77 | POLB (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2092210 | 0.77 | POLB (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102557969-B | Cyclic ketone derivatives and applications thereof as developers and aggregation inhibitors of amyloid protein sediments and neurofibrillary tangles | USTC UNIV SCIENCE TECH CN | 2015-03-18 | — | — | CN | claimed |
| US-7070628-B2 | Composition for the dyeing of human hair | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2006-07-04 | — | — | US | claimed |
| US-7070627-B2 | Composition for the dyeing of human hair | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2006-07-04 | — | — | US | claimed |
| US-7056352-B2 | Composition for the dyeing of human hair | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2006-06-06 | — | — | US | claimed |
| EP-1438948-B1 | Composition for the dyeing of human hair | KPSS KAO GMBH (DE) | 2005-10-19 | — | — | EP | claimed |
| EP-1374841-B1 | Composition for dyeing of human hair | KPSS KAO GMBH (DE) | 2005-10-19 | — | — | EP | claimed |
| EP-1374840-B1 | Composition for the dyeing of human hair | KPSS KAO GMBH (DE) | 2005-10-19 | — | — | EP | claimed |
| EP-1380285-B1 | Composition for the dyeing of human hair | KPSS KAO GMBH (DE) | 2005-10-19 | — | — | EP | claimed |
| EP-1378229-B1 | Composition for the dyeing of human hair | KPSS KAO GMBH (DE) | 2005-10-12 | — | — | EP | claimed |
| US-6852133-B2 | Composition for the dyeing of human hair | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2005-02-08 | — | — | US | claimed |
| WO-1998019661-A1 | COLORANTS FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | claimed |
| WO-1998017234-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 1998-04-30 | — | — | WO | claimed |
| WO-1998017235-A1 | MEANS AND METHOD FOR TINTING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-04-30 | — | — | WO | claimed |
| EP-0634165-B1 | Oxidative dying composition for keratinous fibers containing a para-aminophenol, a meta-aminophenol and a 2-substituted para-aminophenol | OREAL (FR) | 1997-09-24 | — | — | EP | claimed |
| EP-0667143-B1 | Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol | OREAL (FR) | 1996-10-09 | — | — | EP | claimed |
| EP-0667143-A1 | Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol | L'OREAL (FR) | 1995-08-16 | — | — | EP | claimed |
| EP-0634165-A1 | Keratinous fibers oxidation dying composition containing a para-aminophenol, a meta-aminophenol and a 2-substituted para-aminophenol | L'OREAL (FR) | 1995-01-18 | — | — | EP | claimed |
| US-4985042-A | New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1991-01-15 | — | — | US | claimed |
| US-4954131-A | Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1990-09-04 | — | — | US | claimed |
| US-4863480-A | OXIDATION COLOR DYES | THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) | 1989-09-05 | — | — | US | claimed |