Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962321 | 0.91 | POLB (0.42) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL2023835 | 0.87 | POLB (0.48) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL2024699 | 0.83 | BID (0.50) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL2021133 | 0.82 | BID (0.52) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL2023252 | 0.82 | BID (0.52) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL15093736 | 0.79 | POLB (0.51) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL29580560 | 0.79 | POLB (0.51) | POLBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL2019462 | 0.78 | POLB (0.58) | POLBSLC16A3HDAC3HDAC4HDAC1 | |
| SCHEMBL2020241 | 0.77 | METAP2 (0.42) | POLBCYSLTR2CYSLTR1SLC16A3TSHR | |
| SCHEMBL2021365 | 0.77 | CLCN2 (0.43) | POLBCLCN2PTGS2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036235-A2 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (ACHE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2009-03-19 | — | — | WO | disclosed |