SCHEMBL3963341

SCHEMBL3963341

NCCCC(=O)NC(c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 8/20 0.58
SLC6A5 Q9Y345 6/20 0.58
CACNA1G O43497 1/20 0.52
PRCP P42785 2/20 0.52
CNR1 P21554 2/20 0.51
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
CNR2 P34972 1/20 0.47
TSHR P16473 1/20 0.47
CACNA2D1 P54289 1/20 0.46
CACNA1B Q00975 1/20 0.46
CACNB1 Q02641 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4001999 0.85 SLC6A9 (0.63) SLC6A9SLC6A5PRCPCNR1CYP2D6
Hydrochloric Acid SCHEMBL2010289 0.84 SLC6A9 (0.62) SLC6A9SLC6A5PRCPCNR1CYP2D6
SCHEMBL7935565 0.79 SLC6A9 (0.63) SLC6A9SLC6A5PRCPCNR1CYP2D6
SCHEMBL22525971 0.79 NPSR1 (0.55) SLC6A9SLC6A5NPSR1TSHRALDH1A1
SCHEMBL27935595 0.79 NPSR1 (0.55) NPSR1TSHRALDH1A1MEN1KMT2A
SCHEMBL9844424 0.77 NPSR1 (0.56) NPSR1TSHRALDH1A1MEN1KMT2A
SCHEMBL18010560 0.77 LMNA (0.70) SLC6A9SLC6A5CNR1CNR2CACNA2D1
SCHEMBL2012318 0.77 SLC6A9 (0.86) SLC6A9SLC6A5CNR1CYP2D6CYP2C9
SCHEMBL9843976 0.75 NPSR1 (0.77) NPSR1CNR2TSHRALDH1A1MEN1
SCHEMBL22525974 0.75 NPSR1 (0.51) SLC6A9SLC6A5NPSR1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009035307-A2 NOVEL COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME FOR INHIBITING PAIN EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2009-03-19 WO disclosed