Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959403 | 0.90 | PDE4A (0.47) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3960150 | 0.89 | PDE4A (0.45) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3963480 | 0.88 | ADORA3 (0.44) | ADORA3 | |
| SCHEMBL3956047 | 0.86 | PDE4A (0.43) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3962755 | 0.85 | PDE8A (0.44) | ADORA3 | |
| SCHEMBL3957713 | 0.85 | PDE4A (0.41) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7208530 | 0.84 | PDE4A (0.55) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3959850 | 0.84 | PDE4A (0.43) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3956364 | 0.83 | ADORA3 (0.43) | ADORA3 | |
| SCHEMBL3954981 | 0.83 | ADORA3 (0.43) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |