Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952614 | 0.89 | ADORA2A (0.49) | ADORA3 | |
| SCHEMBL3963402 | 0.88 | ADORA3 (0.43) | ADORA3 | |
| SCHEMBL3962755 | 0.86 | PDE8A (0.44) | ADORA3P2RX3 | |
| SCHEMBL7208530 | 0.85 | PDE4A (0.55) | ADORA3 | |
| SCHEMBL3960150 | 0.83 | PDE4A (0.45) | ADORA3 | |
| SCHEMBL3957713 | 0.83 | PDE4A (0.41) | ADORA3 | |
| SCHEMBL3956047 | 0.83 | PDE4A (0.43) | ADORA3 | |
| SCHEMBL3963832 | 0.83 | PDE4A (0.43) | ADORA3 | |
| SCHEMBL7205445 | 0.82 | PDE4A (0.54) | ADORA3 | |
| SCHEMBL3963204 | 0.82 | ADORA2A (0.52) | ADORA3CDK1CCNB1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |