Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | USP8 | P40818 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962868 | 0.79 | CNR2 (0.43) | CNR2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1465768 | 0.75 | CNR2 (0.59) | CNR2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1464341 | 0.74 | ALDH1A1 (0.58) | CNR2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL1464404 | 0.72 | KDM1A (0.60) | CNR2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL1465740 | 0.71 | ABL1 (0.62) | CNR2MAPTMEN1KMT2AKDM1A | |
| SCHEMBL3962808 | 0.71 | CNR2 (0.55) | CNR2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1463680 | 0.71 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL1464492 | 0.71 | CNR2 (1.00) | CNR2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1465767 | 0.70 | ALDH1A1 (0.55) | CNR2KDM4ENPSR1CNR1ALDH1A1 | |
| SCHEMBL1464724 | 0.70 | KDM1A (0.62) | CNR2MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |