SCHEMBL396373

SCHEMBL396373

N#CCc1cc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.58
HRH3 Q9Y5N1 1/20 0.46
AHR P35869 1/20 0.46
HRH4 Q9H3N8 1/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
AOC3 Q16853 2/20 0.44
GUSB P08236 1/20 0.43
OPRK1 P41145 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30939452 1.00 LOXL2 (0.58) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL8303047 0.81 LOXL2 (0.55) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL29851915 0.81 LOXL2 (0.58) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL1308753 0.81 LOXL2 (0.58) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL5262099 0.81 LOXL2 (0.58) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL347687 0.81 LOXL2 (0.58) LOXL2HRH3AHRHRH4MTNR1A
Methane SCHEMBL29165338 0.79 LOXL2 (0.56) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL31230610 0.78 LOXL2 (0.55) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL401081 0.77 LOXL2 (0.69) LOXL2HRH3AHRHRH4MTNR1A
SCHEMBL7169246 0.77 LOXL2 (0.69) LOXL2HRH3AHRHRH4MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119924205-A Rhodiola crenulata tissue culture method 中国中医科学院中药研究所 2025-05-06 CN claimed
US-12005253-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2024-06-11 US claimed
CN-117625475-A Culture method, screening method and screening material of microbial metabolite for preventing and treating TMV 湖南省植物保护研究所 2024-03-01 CN claimed
CN-114456401-B Extraction method capable of improving yield of natural rubber of bumper Liu Zhongtian 西北农林科技大学 2023-09-19 CN claimed
US-20230001193-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS BIOPHARMA CREDIT PLC (GB) 2023-01-05 US claimed
CN-114456401-A Extraction method capable of improving yield of natural rubber in periploca sepium 西北农林科技大学 2022-05-10 CN claimed
US-20110262892-A1 METHODS FOR DETECTION OR MEASUREMENT OF VIRUSES AOYAGI KATSUMI 2011-10-27 US claimed
WO-2007094885-A2 IDENTIFICATION OF A NITRILASE FROM B. JAPONICUM BY RATIONAL GENOME MINING AND METHODS OF USE SOUTHERN METHODIST UNIVERSITY (US) 2007-08-23 WO claimed
EP-0967484-B1 METHODS FOR DETECTING OR ASSAYING VIRUS ADVANCED LIFE SCIENCE INST INC (JP) 2007-05-02 EP claimed
EP-0938891-B1 Cosmetic composition containing cinnamic acid and its use OREAL (FR) 2005-01-05 EP claimed
EP-0925779-B1 Cosmetic composition containing cinnamic acid or at least a derivative and its use OREAL (FR) 2004-02-04 EP claimed
EP-0931542-B1 Cosmetic composition containing phloroglucinol OREAL (FR) 2004-01-14 EP claimed
US-6521239-B1 As agent for stimulating the synthesis of skin lipids; beta-naphthoxyacetic acid SOCIETE L'OREAL S.A. (FR) 2003-02-18 US claimed
EP-1039878-B1 USE OF COSMETIC COMPOSITIONS CONTAINING AT LEAST ONE AUXIN OREAL (FR) 2002-09-25 EP claimed
US-20010051172-A1 Use of cinnamic acid, or of at least one of its derivatives in a cosmetic composition BRETON LIONEL (FR) 2001-12-13 US claimed
US-20010046509-A1 Use of cinnamic acid or of its derivatives in a cosmetic firming composition BRETON LIONEL (FR) 2001-11-29 US claimed
US-6267971-B1 APPLYING COSMETIC COMPRISING CINNAMIC ACID OR DERIVATIVE FOR REDUCING SIGNS OF SKIN AGING SOCIETE L'OREAL S.A. (FR) 2001-07-31 US claimed
US-6264962-B1 STIMULATION OF SKIN LIPID SYNTHESIS; MOISTURIZATION SOCIETE L'OREAL S.A. (FR) 2001-07-24 US claimed
US-6054137-A A THERAPEUTIC TREATMENT FOR STIMULATING PROLIFERATION OF HUMAN KERATINOCYTES AND FOR SKIN DISORDERS SOCIETE L'OREAL S.A. (FR) 2000-04-25 US claimed
EP-0967484-A1 METHODS FOR DETECTING OR ASSAYING VIRUS Advanced Life Science Institute, Inc. (JP) 1999-12-29 EP claimed