Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BMX | P51813 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960170 | 0.85 | BTK (0.56) | BTKBMX | |
| SCHEMBL3965260 | 0.83 | BTK (0.46) | BTKEGFRBMXJAK3 | |
| SCHEMBL1321976 | 0.83 | BTK (0.57) | BTKEGFRBMXJAK3 | |
| SCHEMBL3960660 | 0.83 | BTK (0.39) | BTK | |
| SCHEMBL3964069 | 0.81 | BTK (0.44) | BTKEGFRBMXJAK3 | |
| SCHEMBL1323095 | 0.81 | BTK (0.69) | BTKEGFRBMXJAK3 | |
| SCHEMBL9984224 | 0.81 | BTK (0.49) | BTK | |
| SCHEMBL1323121 | 0.81 | BTK (0.69) | BTKEGFRBMXJAK3 | |
| SCHEMBL1323037 | 0.75 | BTK (0.74) | BTKEGFRBMXJAK3 | |
| SCHEMBL1323329 | 0.74 | BTK (0.73) | BTKEGFRBMXJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081923-A1 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI Pharmaceuticals, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008033854-A1 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI PHARMACEUTICALS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |