Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 12/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464912 | 0.86 | HTT (0.57) | RORCHTTLMNAKDM4ECNR2 | |
| SCHEMBL1465876 | 0.83 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL12095681 | 0.83 | RORC (0.44) | RORCHTTLMNATMIGD3ADORA1 | |
| SCHEMBL4011997 | 0.82 | CNR2 (0.53) | RORCCNR2CNR1TMIGD3ADORA1 | |
| SCHEMBL1464790 | 0.82 | TMIGD3 (0.61) | RORCHTTLMNAKDM4ECNR2 | |
| SCHEMBL3961824 | 0.80 | HTT (0.32) | RORCHTTLMNAKDM4ECNR2 | |
| SCHEMBL1464045 | 0.78 | TMIGD3 (0.56) | RORCHTTLMNAKDM4ECNR2 | |
| SCHEMBL1464291 | 0.76 | TMIGD3 (0.53) | RORCHTTLMNAKDM4ETMIGD3 | |
| SCHEMBL1464626 | 0.75 | TMIGD3 (0.50) | RORCHTTLMNAKDM4ECNR2 | |
| SCHEMBL1464962 | 0.75 | CNR2 (0.47) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |