Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.53 |
| ▸ | CNR1 | P21554 | 6/20 | 0.53 |
| ▸ | GCK | P35557 | 7/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619549 | 0.88 | TMIGD3 (0.53) | CNR2CNR1GCKTMIGD3ADORA1 | |
| SCHEMBL4012682 | 0.87 | CNR2 (0.42) | CNR2CNR1GCKTMIGD3ADORA1 | |
| SCHEMBL1620900 | 0.85 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL1620978 | 0.83 | ADORA1 (0.59) | CNR2CNR1GCKTMIGD3ADORA1 | |
| SCHEMBL3963813 | 0.82 | RORC (0.46) | CNR2CNR1GCKTMIGD3ADORA1 | |
| SCHEMBL1621586 | 0.76 | ADORA1 (0.58) | GCKTMIGD3ADORA1RORC | |
| SCHEMBL1621427 | 0.75 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL775578 | 0.74 | GCK (0.56) | CNR2CNR1GCK | |
| SCHEMBL4017269 | 0.73 | CNR2 (0.50) | CNR2CNR1GCK | |
| SCHEMBL1621911 | 0.73 | CNR2 (0.54) | CNR2CNR1GCKTMIGD3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |