Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADH5 | P11766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959725 | 0.74 | OPRL1 (0.44) | OPRL1OPRM1PDE4APDE4BPDE4C | |
| SCHEMBL3959475 | 0.73 | OPRL1 (0.46) | OPRL1OPRM1 | |
| SCHEMBL3958965 | 0.72 | OPRL1 (0.45) | OPRL1OPRM1 | |
| SCHEMBL242117 | 0.72 | OPRL1 (0.45) | OPRL1OPRM1 | |
| SCHEMBL3650162 | 0.72 | POLB (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30558759 | 0.72 | ALDH1A1 (0.71) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL240013 | 0.71 | OPRL1 (0.62) | OPRL1OPRM1 | |
| SCHEMBL242124 | 0.71 | OPRL1 (0.47) | ALDH1A1OPRL1OPRM1 | |
| SCHEMBL3959633 | 0.71 | OPRL1 (0.51) | PDE3AOPRL1OPRM1PDE4D | |
| SCHEMBL3651953 | 0.71 | TSHR (0.55) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034062-A1 | COMPOUNDS WHICH INHIBIT THE GLYCINE TRANSPORTER AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034062-A1 | COMPOUNDS WHICH INHIBIT THE GLYCINE TRANSPORTER AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |