Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 18/20 | 0.74 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150278 | 0.89 | ESR2 (0.78) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL2150282 | 0.89 | ESR2 (0.78) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL18258347 | 0.85 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28158911 | 0.85 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18980759 | 0.81 | ESR2 (0.50) | ESR2MAPT | |
| SCHEMBL718300 | 0.81 | ESR2 (0.50) | ESR2CYP3A4CYP2D6CYP2C9MAPT | |
| SCHEMBL715319 | 0.81 | ESR2 (0.50) | ESR2MAPT | |
| SCHEMBL714856 | 0.81 | ESR2 (0.50) | ESR2MAPT | |
| SCHEMBL3668278 | 0.81 | ESR2 (0.50) | ESR2MAPT | |
| SCHEMBL17996691 | 0.81 | ESR2 (0.50) | ESR2CYP3A4CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850206-B2 | S1P and/or ATX modulating agents | BIOGEN MA INC. (US) | 2017-12-26 | — | — | US | disclosed |
| EP-2925721-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2017-06-07 | — | — | EP | disclosed |
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-7569727-B2 | N-{(4-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propoxy}-phenyl)-[(E)-ethoxyimino]-methyl}-2,2,2-trifluoroacetamide; exhibit valuable preventive and/or curative activity even at low rates of concentration, while being well tolerated by warm-blooded animals, fish and plants | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| EP-2082005-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | Pleotint, L.L.C. (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-2080752-A1 | Pesticidally active ketone and oxime derivatives | Syngenta Participations AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20060128670-A1 | Pesticidally active ketone and oxime derivatives | SYNGENTA CROP PROTECTION, INC. | 2006-06-15 | — | — | US | disclosed |
| EP-1638924-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | Syngenta Participations AG (CH) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113273-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | CHRM2, FOXO3, CHRM1 | ESR2 1035/4885ESR1 2109/4885CYP3A4 428/4885 |
| US-20060128670-A1 | Pesticidally active ketone and oxime derivatives | CHRM2, CHRM1, DDT | ESR2 1127/4885ESR1 2554/4885CYP3A4 445/4885 |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | CHRM2, FOXO3, CHRM1 | ESR2 1035/4885ESR1 2109/4885CYP3A4 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.