Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 5/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650835 | 0.74 | PIM3 (0.41) | HTTMAP3K5PAK1NCOA1SMN1; SMN2 | |
| SCHEMBL3960229 | 0.72 | HTT (0.41) | HTTMAP3K5PAK1NCOA1SMN1; SMN2 | |
| SCHEMBL23771325 | 0.70 | ALDH1A1 (0.50) | HTTMAP3K5PAK1NCOA1SMN1; SMN2 | |
| SCHEMBL27113483 | 0.67 | HTT (0.54) | HTTMAP3K5PAK1NCOA1SMN1; SMN2 | |
| SCHEMBL4214823 | 0.67 | CDK1 (0.35) | HPGDCDK2CDK1CCNB1CCNA2 | |
| SCHEMBL27430993 | 0.62 | POLA1 (0.39) | HTTMAP3K5SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28278903 | 0.62 | DAO (0.40) | HTTSMN1; SMN2ALDH1A1HPGDPDPK1 | |
| SCHEMBL4419598 | 0.61 | PAK1 (0.60) | HTTMAP3K5PAK1NCOA1SMN1; SMN2 | |
| SCHEMBL10441259 | 0.61 | ALDH1A1 (0.38) | HTTMAP3K5PAK1NCOA1SMN1; SMN2 | |
| SCHEMBL9229551 | 0.61 | KDM5A (0.33) | HTTMAP3K5ALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034411-A1 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-03-19 | — | — | WO | disclosed |