Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HBB | P68871 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 3/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964554 | 0.74 | HTT (0.40) | NPC1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL23771325 | 0.68 | ALDH1A1 (0.50) | KDM4ENPC1ALDH1A1TP53NCOA3 | |
| SCHEMBL3960229 | 0.67 | HTT (0.41) | NPC1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL7028832 | 0.63 | CYP1A2 (0.43) | PIM3KDM4ENPC1ALDH1A1CYP2C19 | |
| SCHEMBL27113483 | 0.62 | HTT (0.54) | NPC1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL4214823 | 0.62 | CDK1 (0.35) | LMNABLM | |
| SCHEMBL4374750 | 0.61 | SMN1; SMN2 (0.34) | KMT2AALDH1A1SMN1; SMN2MAPT | |
| Hypoxanthine SCHEMBL10787830 | 0.61 | ALDH1A1 (0.72) | KDM4ENPC1ALDH1A1CYP2C19CDC7 | |
| SCHEMBL6579717 | 0.61 | MEN1 (0.51) | KDM4EMEN1KMT2AALDH1A1HBB | |
| SCHEMBL8558130 | 0.61 | NOS2 (0.44) | KDM4ENPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185557-A2 | PERHARIDINES AS CDK INHIBITORS | Centre National De La Recherche Scientifique (FR) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009034475-A2 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-03-19 | — | — | WO | disclosed |