Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568761 | 0.91 | PPARA (0.51) | CYP4F2CYP4A11PPARAPPARGBCHE | |
| SCHEMBL4568906 | 0.89 | MAPK1 (0.50) | BCHECYSLTR2CYSLTR1TSHRMAPK1 | |
| SCHEMBL2208855 | 0.87 | TAAR1 (0.45) | PPARAPPARGBCHETAAR1 | |
| SCHEMBL2205362 | 0.86 | MAOB (0.48) | BCHECYSLTR2CYSLTR1TAAR1TSHR | |
| SCHEMBL20318730 | 0.85 | PPARA (0.49) | PPARAPPARGBCHE | |
| SCHEMBL13881720 | 0.84 | CHRM2 (0.48) | PPARAPPARGBCHECHRM2CHRM1 | |
| SCHEMBL25818121 | 0.83 | BCHE (0.43) | PPARAPPARGBCHE | |
| SCHEMBL327462 | 0.83 | PPARA (0.46) | CYP4F2CYP4A11PPARAPPARGCHRM2 | |
| SCHEMBL25819160 | 0.83 | NOS1 (0.47) | BCHE | |
| SCHEMBL18539787 | 0.82 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |